Although outbreaks of infections with Pseudomonas aeruginosa pseu extra-mural have been described, this germ is not pathogenic in the immune competent host. For against, it is a major agent of nosocomial infections, especially in the ICU, where he is responsible for pneumonia, urinary or skin infections and bacteremia. Some studies show that nosocomial infections due to Pseudomonas aeruginosa are associated with shorter hospital stays and higher mortality than infections due to other germs.
Pseudomonas aeruginosa can be part of physiological flora of humans, especially in the skin, particularly of the nasopharynx and stool from 2.6 to 24% of people examined. At the hospital, patients may also colonize from exogenous sources, including from other patients colonized or infected. In this case, the germs are probably transmitted primarily through the hands of personnel. infections Pseudomonas aeruginosa are sometimes in the form of outbreaks.
[...] In total, eighteen strains of these patients and sixteen samples were types of environment. The same type was found in patients and 3 (cluster 1). A second type was found in patients and 6 (cluster 2). The strains of the other five patients to 11) had a single type. In one patient (patient two different strains were found. None of the sixteen strains of environmental samples did electrophoretic profile identical to strains found in patients. Patients and 3 (cluster have all stayed together at some point in the same department of SI, mostly contiguous manner. [...]
[...] Since the beginning of the investigation of this outbreak, no new infection has been detected by our microbiology laboratory and no patient readmissions were due to infectious problems occur following a review Urodynamics. Conclusion The alert threshold microbiological after invasive examination should be low. This requires close collaboration between different partners, particularly the microbiology laboratory, the prescribers and those responsible to hospital hygiene. Indeed, the readiness to begin an investigation allows to control the magnitude of an epidemic that may have significant consequences in terms of morbidity and costs. [...]
[...] In this regard, a recent study showed that the risk of developing resistance to one anti-Pseudomonas antibiotic treatment was very different from one antibiotic to another (in ascending order ceftazidime [...]
[...] Methods and patients Patients who stayed in the ICU during the month of January 1997 and at least one microbiological sampling positive for Pseudomonas aeruginosa were investigated. Concomitant diseases and antibiotic treatment were recorded. Transfers during hospitalization were noted. Of water and environment have been made. The method of pulsed-field gel electrophoresis (pulsed field gel electrophoresis or PFGE) was used for molecular typing of support tasks after DNA extraction and digestion by two restriction enzymes (XbaI, Speyer). A strains been considered resistant if it was resistant to more than one class of antibiotics active against P. [...]
[...] Outbreak of gut colonization by Pseudomonas aeruginosa in immunocompromised children undergoing total digestive decontamination: analysis by pulsed- field electrophoresis. J Clin Microbiol 1991; 29: 2068- Hancock RE. Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative gram-negative bacteria. Clin Infect Dis 1998; 27 (Suppl. S93- Carmeli Troillet Eliopoulos GM, et al. Emergence of antibiotic- resistant Pseudomonas aeruginosa: Com-parison of risks associated with different antipseudomonal agents. Antimicrobial Agents and Chemotherapy 1999, 43: 1379- Blanc DS, Siegrist HH, Sahli Francioli P. Ribotyping of Pseudomonas aeroginosa: Discriminatory power and usefulness as a tool for epidemiological studies. [...]
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