Scientific and Technical Concepts in Nuclear Medicine

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[...] Scientific and Technical Concepts in Nuclear Medicine Introduction Nuclear Medicine is an essential branch of modern healthcare that involves radioactivity for imaging, diagnosis, and treatment. It consists of administering radiopharmaceuticals or substances labeled with radioactive isotopes, which emit radiation detectable by specialized imaging devices. Such techniques allow for the visualization of organ function in ways that conventional methods cannot. According to Mayo Clinic 2020, Nuclear Medicine is used therapeutically to target and destroy diseased tissues, such as cancer cells, in areas inaccessible to conventional surgery. [...]

[...] Applications in Diagnosis and Treatment Nuclear Medicine has diverse applications, with notable examples including: 1. Positron Emission Tomography (PET) Scans 2. PET scans are instrumental in oncology, neurology, and cardiology. For instance, they detect metabolic activity in cancer cells or plaque accumulation in Alzheimer's. 3. Gallium Scans 4. Gallium-67 is used to identify infections, inflammation, and lymphomas. This scan is particularly effective in diagnosing sarcoidosis and fever of unknown origin. 5. Therapeutic Use of Radiopharmaceuticals 6. Radioiodine therapy treats thyroid disorders, such as hyperthyroidism and thyroid cancer. [...]

[...] Ethical, Legal, Social, and Epistemological Considerations of Radiation Exposure. Springer EBooks, 629-662. https://doi.org/10.1007/978-3-031-18810-7_12 Kostos, L., Buteau, J., Yeung, T., Juliana Di Iulio, Xie, J., Cardin, A., Chin, K. Y., Emmerson, B., Owen, K. L., Parker, B. S., Fettke, H., Luc Furic, Azad, A., & Hofman, M. S. (2022). Alphabet: Combination of Radium-223 and [177Lu Lu-PSMA-I&T in men with metastatic castration-resistant prostate cancer (clinical trial protocol). Frontiers in Medicine https://doi.org/10.3389/fmed.2022.1059122 Mayo Clinic. (2020, November 26). Nuclear Medicine Therapy - About nuclear medicine therapy. [...]

[...] H. (2023). Radiochemistry for positron emission tomography. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-36377-4 Sewell, C. A., Sheehan, S. M., Gill, M. S., Henry, L. M., Bucci-Rechtweg, C., Gyamfi-Bannerman, C., Lyerly, A. D., McKinney, L. C., Hatfield, K. P., Baer, G. R., Sahin, L., & Nguyen, C. P. (2022). Scientific, ethical, and legal considerations for including pregnant people in clinical trials. American Journal of Obstetrics and Gynecology, 227(6). [...]