Why are African American Women More Prone to Venous Thromboembolism?

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[...] The research will be carried out in healthcare facilities whose customers mainly consider themselves to be Black American people. - Eligibility criteria 1. Inclusion criteria: Participants will be admitted if they make a self-identification as Black women aged 18-45 years who have a documented past of using hormonal contraceptives. Women with and without a task history of venous thromboembolism (VTE) will be eligible to join. Besides that, the participants should be provided with the ability to offer informed consent and be located in the area of prevalent predominantly Black community health facilities. [...]

[...] Why are African American Women More Prone to Venous Thromboembolism? I. Background and concise literature review Venous thromboembolism, which is the simultaneous existence of deep vein thrombosis (DVT) and pulmonary embolism is a dreadful condition with a fatal outcome even when hormonal contraceptive is utilized. Besides, studies report that the risk of VTE among these African American women who use hormonal birth control pills is higher than the rest of the race/ ethnic groups (Kahn et al., 2023). It can be noted that such a possible situation may also be a result of genetic as well as socioeconomic discrimination, which could be one of the probable causes of the very combination of these two. [...]

[...] Exclusion criteria: The participants will be excluded if they do not self-identify as African Americans and women between 18 and 45 or if they have no documented history of hormonal contraceptives. This patient will be excluded from having a history of VTE before starting hormonal contraceptives as well. Moreover, the study will focus on consenting subjects who are capable and do not necessarily have predominantly black community-based centers. - Data collection methods Quantitative data will be drawn from the electronic health records of the participant's medical records, and we will be concentrating on information related to demographics, contraceptive use history, and VTE events. [...]

[...] Dependent variables: Venous thromboembolism (VTE) events ii. Main independent variables: Hormonal contraceptive use iii. Other independent variables: Genetic factors, socioeconomic status, healthcare access VI. Data analysis Quantitative data will be assessed using descriptive statistics to identify the frequency of VTE in African American women in the age group 18-45 years with hormonal contraceptive use. Discrimination analysis will be comprised of information on events of venous thromboembolism (VTE) in the study population presented as frequencies and percentages. Thematic analysis, which will be used to generalize the data, will be qualitative to find the main themes that are related to risk factors of VTE and the perception among African American women of hormonal contraceptives. [...]

[...] - Research Question Why are African American women more prone to venous thromboembolism when taking hormonal birth control? - Specific Aims Conduct a literature search to identify the causes of VTE risk escalation among African American women who are using hormonal contraceptives. The study aims to explore different measures like immobility, prolonged surgery, and osteoporosis that may increase the risk of thrombosis among this patient population. III. Hypothesis It was hypothesized that VTE, which is the blood clotting in the veins, mostly African American women, may be due to genetic issues along with social factors. [...]