If an organism can remain lean, lifespan is increased--as long as it avoids any excess fat accumulation. But this must be done without diminishing dietary intake. Research attests that those who practice calorie restriction have (in a statistically significant way) better cardiovascular health. Energy is conserved and there is less fat; so less (energy) is required to support the weight. As result, there doesn't have to be so much glucose in the bloodstream. Thus, there are no sticky blocks in the bloodstream because of less fat to oxidize—which results in arteriosclerosis.
[...] Resveratrol and calorie restriction If an organism can remain lean, lifespan is increased--as long as it avoids any excess fat accumulation. But this must be done without diminishing dietary intake. Research attests that those who practice calorie restriction have (in a statistically significant way) better cardiovascular health. Energy is conserved and there is less fat; so less (energy) is required to support the weight. As result, there doesn't have to be so much glucose in the bloodstream. Thus, there are no sticky blocks in the bloodstream because of less fat to oxidize—which results in arteriosclerosis. [...]
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